The routine traffic stop that ends in tragedy. The spy who spends years undetected at the highest levels of the Pentagon. The false conviction of Amanda Knox. Why do we so often get other people wrong? Why is it so hard to detect a lie, read a face or judge a stranger's motives? Through a series of encounters and misunderstandings - from history, psychology and infamous legal cases we're takesn on an intellectual adventure into the darker side of human nature, where strangers are never simple and misreading them can have disastrous consequences.